منابع مشابه
Adaptation of the [3H]Hypoxanthine Uptake Assay for In Vitro-Cultured Plasmodium knowlesi Malaria Parasites.
The zoonotic malaria parasite Plasmodium knowlesi has recently been established in continuous in vitro culture. Here, the Plasmodium falciparum [(3)H]hypoxanthine uptake assay was adapted for P. knowlesi and used to determine the sensitivity of this parasite to chloroquine, cycloguanil, and clindamycin. The data demonstrate that P. knowlesi is sensitive to all drugs, with 50% inhibitory concent...
متن کاملUptake of methotrexate-3H by rabbit kidney slices.
Methotrexate-3H (MTX-3H) was accumulated against a con centration gradient by renal cortical slices. This accumulation was energy dependent, inhibited by metabolic inhibitors, Diamox, and high concentrations of ouabain. Several folie acid analogs containing the pteridine ring were inhibitors of this accumulation while certain weak organic acids were less striking inhibitors. This suggests that ...
متن کاملDeposition of [3H]cocaine, [3H]nicotine, and [3H]flunitrazepam in mouse hair melanosomes after systemic administration.
Microautoradiography was employed to show that association of drugs from the serum directly with forming hair pigment is a primary pathway of deposition into the hair. After systemic administration of [3H]flunitrazepam, [3H]nicotine, and [3H]cocaine, association of all three drugs with melanin in the forming hair was observed within minutes of dosage. Sebum was determined to be an insignificant...
متن کاملThymidine-3h Uptake by Satellite Cells of Regenerating Skeletal Muscle
The satellite cell (6) is a mononucleated cell that is wedged between the multinucleated muscle syncytium and the basal membrane of the myofiber. These cells are described in skeletal muscle of amphibians (6, 7) and mammals (3, 12-14). From data in the literature it is clear that satellite cells are most abundant during embryonic life, though it is not obvious that they participate in the norma...
متن کاملTrimetazidine increases [3H]glucose uptake in rat brain.
Trimetazidine, a clinically effective antianginal agent with no negative inotropic or vascular properties, acts by optimizing cardiac energy metabolism through inhibition of free fatty acid oxidation, shifting substrate utilization from fatty acids to glucose. Up to now there has been no study associating trimetazidine's effect on metabolic processes with glucose utilization in the mammalian br...
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ژورنال
عنوان ژورنال: BIO-PROTOCOL
سال: 2013
ISSN: 2331-8325
DOI: 10.21769/bioprotoc.887